Catalog Number - 68040-P21-PG1

Cogent NP Amino Prep Guard Column Cartridges are packed with the same propyl amino bonded stationary phase used in Cogent NP Amino preparative columns. Manufactured on high-purity silica with an amino-functionalized propyl ligand, these guard cartridges protect the preparative column from particulates, strongly retained contaminants, and sample matrix components that can reduce column performance and service life. The chemistry is suitable for both Normal Phase and HILIC applications and provides the same USP L8 selectivity as the analytical bed it protects.

68040-P21-PG1 is a preparative guard column cartridge packed with 10 µm NP Amino particles featuring a 100 Å pore size in a 21.2 mm ID x 10 mm format. Installed ahead of the preparative column, it captures contaminants before they reach the analytical bed, helping maintain chromatographic performance, improve reproducibility, and extend column lifetime in demanding purification applications.

This guard cartridge is designed specifically for use with 21.2 mm ID Cogent NP Amino preparative columns and is housed in durable stainless-steel hardware with stainless-steel frits for reliable operation under preparative flow conditions.

Key Benefits

• NP Amino stationary phase

• USP L8 equivalent chemistry

• Propyl amino bonded phase

• High-purity silica support

• Suitable for Normal Phase chromatography

• Suitable for HILIC applications

• Protects preparative columns from particulates and contaminants

• Helps maintain column efficiency and reproducibility

• Extends preparative column lifetime

• Stainless steel cartridge construction

Typical Applications

• Preparative chromatography

• USP L8 methods

• HILIC separations

• Normal Phase chromatography

• Sugar purification

• Carbohydrate purification

• Organic acid purification

• Pharmaceutical purification

• Sample cleanup prior to preparative separation

• Preparative column protection

Specifications

• Product Type: Preparative Guard Column Cartridge

• Stationary Phase: NP Amino

• USP Classification: L8

• Chromatography Mode: Normal Phase / HILIC

• Bonded Phase: Propyl Amino

• Endcapping: Not Endcapped

• Particle Size: 10 µm

• Pore Size: 100 Å

• Cartridge Dimensions: 21.2 mm ID x 10 mm

• Hardware Material: Stainless Steel

• Frit Material: Stainless Steel

• Quantity: 1 EA

• Brand: Cogent

Guard Column Holder Requirement

• A 21.2 mm ID Prep Guard Column Holder is required for use with this cartridge.

• View the Cogent 21.2 mm ID Prep Guard Column Holder (83000-P21-GH)

Special Order Item Information

• Contact Customer Service for quotation, lead time, and ordering assistance.

• Learn more about Special Order Items and ordering policies.

Important Notes

• Packed and shipped in Normal Phase solvents

• Suitable for both Normal Phase and HILIC chromatographic modes

• Designed for use with 21.2 mm ID NP Amino preparative columns

• Helps protect preparative columns from contamination and premature fouling

• Requires a specialized preparative HPLC system compatible with 21.2 mm ID columns

• This is a Special Order Item

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